CeMSA@HHU (Center for Molecular and Structural Analytics at Heinrich Heine University Düsseldorf) is a service center at the faculty for mathematics and natural sciences at Heinrich-Heine-Universität, which offers service to all researchers of Heinrich Heine University. The service center consists of two devisions, a devision for mass spectrometry and a division for NMR spectroscopy. In 2020 there were more than 250 users from more than 20 research groups from biology, chemistry, pharmacy, physics and the university hospital. Mass Spectrometry: Currently, we provide service using five different mass spectrometers, utilizing different ionization methods (e.g. MALDI, ESI, EI). The separation of the ions is carried out by (triple-) quadrupol, ion trap, or by time-of-flight (TOF/TOF and qTOF). The injection of the samples is either direct (solid or as solution via siringe pump) or via GC or HPLC. NMR Spektroscopy: Currently, we provide service using three different NMR spectrometer (300 MHz, 500 MHz and 600 MHz). The service includes automatic measurements form routine NMR as well as several special experiments (high- and low temperature, DOSY, HOESY, selective experiments, several special nucleus, ...) and support interpretation of the obtained data.