Genomic, Transcriptomic, Proteomics and Metabolomics Facilities

The services offered by the Core Facility of Mass Spectrometric Proteomics includes basic services such as the identification of purified proteins out of a gel matrix or in solution. For scientific cooperations the following methods are offered: - Quantitative differential glycome and proteome analysis in a label-free approach (MS1 based [LFQ], Data Independent Mass Spectrometry [DIA]); - Quantitative differential proteome analysis with labeling (SILAC, TMT); - Chromatographic enrichment / fractionation of biomolecules (pH dependent reversed phase Chromatography, Strong Cation/Anion Exchange Chromatography, Displacement Chromatography); - Mass spectrometry of intact proteins; - Mass spectrometric imaging; - Statistics of MS data; - Interpretation of the results of the MS analysis including gene ontology analysis and text-mining aiming the generation of new hypothesis Additionally, tailored procedures of experiments, data processing and interpretation routes are being developed and discussed in close collaboration with each collaboration partner.