The CECAD Imaging Facility was established as part of a new founded excellence cluster CECAD (Cologne Cluster of Excellence in Cellular Stress Responses in Aging-associated Diseases) and is a joint venture of the Mathematics/Natural Sciences Faculty and the Medical Faculty of the University of Cologne. The aim of our facility is to support scientists in their research concerning light microscopy imaging and their data analysis. The facility is equipped with state-of-the-art light microscopes for cellulrar, molecular and intravital imaging including a big variety of widefield and confocal, a multiphoton as well as two superresolution microscopes. Scientists are trained individually on the equipment best suited for their research approach, afterwards they are able to independently book and use the systems. A team of a technical assistant, two microscopists and a bioinformatician are always available to assist the users. Additionally, two dedicated powerful analysis stations are located within the facility, equipped with different software programs for further data presentation, analysis and deconvolution. More specialized techniques like FRAP, FLIM, laserablation and superresolution are covered by the facility as well.