Details
Microfluidics Core Facility (µFlu CF)


Within the newly established and sole Microfluidics Core Facility at University Heidelberg and surrounding (e.g.: EMBL, DKFZ,
MPI), we support research groups in setting up and running microfluidic experiments. Microfluidic describes the study of liquids
and gases in small channels. The versatility of the chips allows them to be a useful tool for multiple disciplines, such as
medicine, biophysics, chemistry and many more.
We focus on the fabrication of microfluidic chips, which involves the entire
process, starting from the general chip design to the production of the custom tailored device. Besides the Microfabrication,
we support the users with knowledge in conducting the experiments and introducing the users to standard microfluidic technologies.
Given
the infrastructure of the user's lab and the experimental application of the chip, the experiments are either conducted at
the user's laboratory or, after an introduction to the microfluidic set up, at the microfluidic core facility.
Since we are
a very project oriented core facility, there are many discussions with the users through the process, leading to chip alterations
or follow up projects after initial results.
Address: Im Neuenheimer Feld 225
69120 Heidelberg
Baden-Württemberg
Deutschland
To website
69120 Heidelberg
Baden-Württemberg
Deutschland
To website
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Host Institution
Universität Heidelberg, Institute for Molecular Systems Engineering and Advanced Materials (IMSEAM)
Im Neuenheimer Feld 225
69120 Heidelberg
Baden-Württemberg
Deutschland
https://www.imseam.uni-heidelberg.de
Im Neuenheimer Feld 225
69120 Heidelberg
Baden-Württemberg
Deutschland
https://www.imseam.uni-heidelberg.de
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Scientific Domain
Primary Subjects:
- Biology
- Medicine
- Materials Science and Engineering
Secondary Subjects:
- Chemistry
- Physics
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Category
Micro- and Nanotechnology facilities
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Scientific Services
Several techniques are being employed at the microfluidic core facility to deliver high quality microfluidic chips for the
users. To ensure a satisfying outcome for the users, we first set up a general meeting to discuss the final goal of the project
and the necessary design of the chip. Based on the requirements and specifications the chip has to meet, the chips are either
prepared with standard lithography or 3D printing by the staff of the facility.
By using a spin coater, the photoresist is
first distributed on a suitable substrate at the height of choice. With the mask-less Aligner the design is exposed into the
photoresist and developed. With a profilometer the final height of the chip is being determined. The final product is handed
to the user for microfluidic experiments. The facility also owns a 3D printer to generate more complex microfluidic devices.
Users
can also book a microfluidic set up to conduct their experiments at the facility. The set up consist of a light microscope
with 3 fluorescent filter cubes, a high speed camera, a pressure-based flow controller and 4 syringe pumps.
Besides conventional
Microfluidics we also offer support, by means of knowledge and equipment, to generate water-in-oil emulsion off-chip, synthetic
cells or glass-capillary based microfluidic systems.
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Scientific Equipment
- Mask-less Aligner
- 3D printer
- Spincoater
- Cutter plotter
- High speed camera
- Syringe pumps
- Pressure-based Flowsystems
- Light microscopes
- Profilometer
- Laser Cutter
- Emulsifier
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Keywords
- Droplet-based microfluidics
- Continuous flow microfluidics
- Organ-on-Chip Technologies
- Real-time deformation cytometry
- Glass capillary microfluidics
- Small scale DLP 3D Printing
- Synthetic cell production
- Lipidnanoparticle production
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Networks
Health + Life Science Alliance Heidelberg Mannheim
https://www.health-life-sciences.de/?lang=de
https://www.health-life-sciences.de/?lang=de
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Users per annum
Internal Users: 13
External Users in total: 33
External Users: 31
External Users in the EU: 0
External Users outside of EU: 2

