Pluripotent stem cells combined with state of the art cell engineering techniques are unique tools helping scientists pinpointing disease-causing mutations to specific cellular mechanisms enabling the development of novel therapeutic approaches. The mission of the BIH Stem Cell Core Facility is to support basic and translational research by facilitating all aspects of human induced pluripotent stem cell (hiPSC) technology including the derivation, differentiation, genetic editing and distribution of human iPS cell lines. Additionally, the facility provides scientists with state of the art protocols and techniques for proper handling and manipulation of hPSC and also the infrastructure for incomming scientists. Furthermore, the Core Facility regularly organizes hands-on training courses of standardized pluripotent stem cell culture techniques. Project specific service fees will be calculated individually after project consultation