Genomic, Transcriptomic, Proteomics and Metabolomics Facilities

The Analytics Core Facility Essen (ACE) offers the following services for internal and external users: (1.) Recording of mass spectra in the direct injection mode with the ESI ionization technique and optionally exact mass determination. (2.) UHPLC/HPLC-MS measurements (ESI) (3.) Mass determination of intact proteins or protein complexes (denaturing or native) (4.) Mass spectrometry-based protein identification of affinity purified proteins or complex full proteome samples either in a qualitative or quantitative fashion (either by label-free quantification or by using tandem mass tags (TMT) (5.) Identification and optionally quantification of post-translational modifications (e.g. phosphorylation, ubiquitination, methylation) (6.) Analysis of crosslinked proteins (CrossLinking-MS) (7.) Basic data analysis and delivery of the overview spectra or initial results (8.) For all proteomics projects: scientific data interpretation by ACE staff members.