Genomic, Transcriptomic, Proteomics and Metabolomics Facilities

Section Proteomics: The BayBioMS offers the complete methological spectrum of modern proteomics: - protein identification by LC-MS/MS from all organisms with sequenced genomes; - relativ protein quantification using common approaches (SILAC, TMT, label-free); - absolute protein quantification using isotopically labeled reference peptides as well as label-free protein abundance estimations; - analysis of post-translation modifications (phosphorylation, acetylation etc.); - deep fractionations of peptides using different fractionation technologies (e.g. high pH reverse phase); - analysis of protein complexes; - project planning, execution, data analysis and publication Section Metabolomics: The BayBioMS offers the complete methodological spectrum of mordern metabolomics: - non-targeted metabolite profiling using TOF-MS in biological samples; - identification of Phase I oder Phase II reaction products or other biotransformations; - quantitative analysis of metabolites for example by means of stable isotope dilution analysis; - project planning, execution, data analysis and publication